Tirzepatide 10mg is a synthetic peptide analog that acts as a dual agonist of GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptors. It is currently under investigation for its potential therapeutic benefits in obesity, insulin resistance, and type 2 diabetes mellitus.
In preclinical and clinical research, Tirzepatide has demonstrated synergistic metabolic effects, combining glycemic control with appetite suppression and weight reduction. The 10mg vial is typically reconstituted with bacteriostatic water and used in laboratory settings for mechanistic studies, receptor binding assays, and pharmacodynamic modeling.
Key Features
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Dual incretin agonist (GIP + GLP-1 receptor)
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High purity (≥98%) suitable for research applications
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Supports studies on insulin secretion, appetite regulation, and energy balance
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Stable lyophilized form for easy storage and handling
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Ideal concentration for dose-response and metabolic research
Research Applications
Tirzepatide 10mg is primarily used in experimental research, including:
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Studies on glucose metabolism and insulin sensitivity
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Investigation into obesity models and fat mass reduction
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Preclinical models evaluating pancreatic beta-cell function
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Evaluation of cardiometabolic parameters in animal studies
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Combination therapy research with other metabolic agents
Storage & Handling
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Store lyophilized peptide at -20°C
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Reconstituted solution should be refrigerated at 2°C–8°C and used within 30 days
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Protect from light and avoid repeated freeze-thaw cycles
Disclaimer
Tirzepatide 10mg is intended strictly for laboratory research use only. It is not a drug, food, or cosmetic and must not be used in humans or animals outside of approved research environments. Misuse may be dangerous and is a violation of regulatory laws.
How to Reconstitute Tirzepatide
Materials Needed:
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Tirzepatide 10mg lyophilized vial
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Bacteriostatic Water (0.9% benzyl alcohol in sterile water) or Sterile Water for Injection (SWFI)
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Alcohol swabs
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1mL or 3mL sterile syringe with needle
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Mixing vial (optional but preferred for precise handling)
Step-by-Step Instructions:
1. Choose a Reconstitution Volume
Most researchers use 1–2mL of diluent depending on the desired concentration.
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1mL yields 10mg/mL concentration
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2mL yields 5mg/mL concentration
2. Sanitize
Wipe the rubber stoppers of both the Tirzepatide vial and the bacteriostatic water vial with alcohol swabs.
3. Draw the Diluent
Use a sterile syringe to draw 1–2mL of bacteriostatic water or sterile water.
4. Add Diluent Slowly
Insert the needle into the Tirzepatide vial and slowly release the water down the side of the vial (not directly onto the powder).
This prevents foaming or peptide denaturation.
5. Swirl Gently
Do not shake. Gently swirl or roll the vial between your fingers until the powder is fully dissolved.
The solution should be clear and particle-free.
Tirzepatide 10mg mL
Tirzepatide 10mg mL is a potent dual GIP and GLP-1 receptor agonist available in a high-purity injectable format, standardized to 10 milligrams per milliliter. This concentration offers precise, consistent dosing in metabolic research studies exploring glucose regulation, insulin sensitivity, appetite modulation, and weight control.
Tirzepatide’s unique structure allows it to bind and activate both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors, mimicking the action of native incretin hormones with enhanced potency and longer duration.
Frequently Asked Questions (FAQs) – Tirzepatide 10mg
1. What is Tirzepatide 10mg?
Tirzepatide 10mg is a synthetic peptide used in preclinical and laboratory research. It functions as a dual GIP and GLP-1 receptor agonist, making it useful for studies on glucose metabolism, insulin regulation, appetite control, and weight modulation.
2. What does “dual agonist” mean in this context?
Tirzepatide is called a dual agonist because it binds to and activates both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. This dual action is thought to enhance metabolic signaling in models of insulin resistance and obesity.
3. How is Tirzepatide 10mg supplied?
It is typically supplied as a lyophilized powder in a 10mg vial. Researchers reconstitute it using bacteriostatic water or sterile water for injection to achieve a desired concentration, often 10mg/mL or 5mg/mL.
4. How should Tirzepatide 10mg be stored?
- Before reconstitution: Store the vial in a freezer at -20°C
- After reconstitution: Keep refrigerated at 2°C to 8°C
- Avoid light and repeated freeze-thaw cycles. Use within 30 days of reconstitution.
5. What are the typical research applications?
Tirzepatide 10mg is used in studies related to:
- Type 2 diabetes models
- Weight loss and obesity research
- Insulin secretion dynamics
- Beta-cell function and pancreatic health
- Comparative metabolic efficacy vs. GLP-1 analogs
6. What is the recommended dosage for research?
There is no standardized dose, as it depends on the species, research protocol, and study objective. However, common ranges in rodent models are 2.5mg to 10mg per week, often administered subcutaneously. Always refer to peer-reviewed studies or protocol guidelines when determining dosage.
7. Can Tirzepatide 10mg be used in humans or pets?
No. Tirzepatide 10mg is sold strictly as a research chemical. It is not intended for human or veterinary use, and any off-label application is prohibited.
8. Is Tirzepatide stable after reconstitution?
Yes, if stored properly. Once reconstituted, the solution remains stable for up to 30 days in refrigeration (2°C to 8°C). Discard if discoloration or particulates appear.
9. What precautions should be taken when handling it?
- Use aseptic technique
- Wear lab gloves and protective equipment
- Handle in a certified biosafety cabinet, if applicable
- Dispose of all materials following biosafety and local regulations
10. Is COA (Certificate of Analysis) available?
Yes. Reputable suppliers provide a Certificate of Analysis (COA) and purity documentation (usually ≥98%) for each batch of Tirzepatide 10mg.
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