Syn TC is a patented synthetic peptide complex specifically engineered to boost collagen production in the skin. Designed to target all five major types of collagen (I, III, IV, VII, and XVII), Syn-TC enhances the skin’s structural integrity, visibly improving firmness, smoothness, and elasticity. It is widely used in high-end anti-aging and dermal repair formulations to reduce the appearance of fine lines and wrinkles, delivering a smoother, more youthful-looking complexion. Thanks to its clinically proven efficacy and rapid results, Syn-TC is a popular active ingredient among dermatologists, cosmetic chemists, and skincare professionals.
collagen peptides
Collagen peptides are short chains of amino acids derived from the hydrolysis of collagen, the primary structural protein in skin, bones, tendons, and connective tissues. Easily absorbed by the body, collagen peptides are known for their ability to support skin elasticity, joint health, and muscle recovery. In skincare, they help stimulate natural collagen production, improving firmness, hydration, and reducing the appearance of wrinkles. In supplements, they are often marketed for anti-aging, joint support, and overall tissue repair, making them a key ingredient in both beauty and wellness routines.
Syn Ake Serum
Syn Ake Serum is a cutting-edge anti-aging skincare product formulated with Syn-Ake, a synthetic tripeptide that mimics the effects of Waglerin-1, a peptide found in temple viper venom. This advanced ingredient works by temporarily inhibiting muscle contractions, helping to reduce expression lines and dynamic wrinkles—similar to how Botox works, but without injections. Syn-Ake Serum is often used as a topical solution for smoothing forehead lines, crow’s feet, and frown lines, delivering visibly firmer, more relaxed skin. It’s a favorite among users seeking a non-invasive alternative to neuromodulator treatments in their daily skincare routine.
Syn-TC Complex 75%
Syn-TC Complex 75% is a high-strength formulation of the Syn TC peptide blend, containing 75% concentration for intensive anti-aging performance. This advanced cosmetic ingredient targets five critical types of collagen—Types I, III, IV, VII, and XVII—to deliver visibly firmer, smoother, and more youthful-looking skin.
By boosting the skin’s structural matrix, Syn-TC Complex 75% helps:
- Reduce fine lines and deep wrinkles
- Improve skin texture and elasticity
- Restore a firm, contoured appearance
- Support long-term dermal regeneration
Ideal for use in professional-grade serums, eye treatments, and facial creams, this concentrated version offers faster and more pronounced results in clinical and at-home skincare routines.
One – 2 dram* (1/4oz) amber glass dropper bottle of Syn-TC. *You may choose a larger size.
Direction sheet for mixing
Skin smoothing products, High performing facial, Anti-ageing formulas, Anti-wrinkle and anti-photoaging solutions, Plumping beauty products.
You have the option to apply your actives directly into any product that you currently have. *Dare we suggest adding these actives into our Derma Snap 8LM or GABA creams – which are both already teaming with penetration enhancers and other proven actives????
Each active will come in a 7.5ml glass amber bottle with a dropper for ease of usage. The percentage of actives is very high, and will only be mixed with 2 penetrating actives and a preserving ingredient. Our Neuro-Peptide-Actives are SUPER CHARGED to allow deep penetration into your skin.
Total Collagen Care With Syn(R)-TC
Looking young and beautiful is widely accepted to be a source of professional success and personal happiness. Collagens play a major role in the skin, ensuring proper functionality and thus perfectly smooth, young-looking skin. During the process of ageing our body’s natural production of collagen in the skin decreases, and as its functionality is reduced, typical signs of ageing become visible. Whilst traditional anti-ageing approaches mostly focus on dermal collagen type I, SYNR-TC follows a more holistic approach that focuses on total collagen care. A particular focus is set on collagen type III – the so-called youth collagen – that is known for its skin smoothing properties, especially in young skin. Additional focus is set on the collagens of the dermal-epidermal junction (DEJ), especially on collagen IV, VII and XVI, the so-called anchoring collagens that are essential for skin functionality and support skin firmness
Unique Product Features
Patented synthetic Tri- and Tetrapeptide technologyCombines best performance in a tailor made peptide complexSYN(R)-TC significantly increases in vitro the amount of collagens to facilitate their unique contribution to beautiful smooth skin.
Benefits
Skin is smoother with a softer touch and improved overall young looking appearance.Skin appears plumperSkin appears firmerSkin elasticity is improvedAppearance of fine lines and wrinkles is visibly reduced.
Cosmetic Application
Skin smoothing products High performing facialAnti-ageing formulasAnti-wrinkle and anti-photoaging solutions Plumping beauty products.
INCI Name:
Glycerin, Aqua, Tetradecyl aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Palmitoyl Tripeptide-5, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine.
Suggested Concentration
2.5% SYN(R)-TC *Ours is a 75% Solution (7% at 3 drops).
Collagens are the most abundant proteins in the skin, making up 75 percent of the skin proteins. Collagens are mainly responsible for the skin’s strength and smoothness as they provide structure and firmness. However, over time collagen levels decrease and their proper function is reduced. SYNR-TC is a synthetic peptide-based complex tailor-made for optimal activity. In vitro, SYNR-TC peptides increase the formation of undamaged, stable and homogeneous collagens to facilitate their unique contribution to beautiful smooth skin.
The picture (above) shows the tight interaction between the dermal collagens I and III and the DEJ collagens IV, VII, and XVII. Each of these collagens varies in structure and functionality. DSM’s key finding was that in order to ensure highest collagen level and functionality in vitro different tailor-made peptide sequences have to be combined. SYN(R)-TC is a combination of those peptide sequences that work in vitroon dermal collagens I and III as well as on the DEJ collagens IV, VII, and XVII – all in one product.
Directions:
SEE detailed direction sheets in product photos (top of page). Apply this powerful elixir to your problem areas 2x daily before all other serums or creams. Expect to see noticable changes within 30-45 days.
Ingredients
Purified Water, Glycerin, Ethoxydiglycol, Palmitoyl Tripeptide 5, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Dipeptide-5 Diaminohydroxybutyrate, Magesium Chloride, Polysorbate 20, Benzyl Alcohol, Methylisothiazolinone.
Frequently Asked Questions about SynTC
1. What is Syn TC?
Syn TC is a patented synthetic peptide complex developed by DSM that targets skin aging. It’s designed to boost the production of multiple types of collagen (I, III, IV, VII, and XVII) to improve skin firmness, smoothness, and overall texture.
2. What does Syn TC do for the skin?
Syn TC helps:
- Enhance collagen density and quality.
- Visibly reduce fine lines and wrinkles.
- Improve skin smoothness and resilience.
- Restore a more youthful, firm complexion.
3. Is Syn TC suitable for all skin types?
Yes. Syn TC is generally well-tolerated by all skin types, including sensitive skin. However, like any active ingredient, it should be patch-tested before full application to rule out irritation or sensitivity.
4. How is Syn TC used in skincare products?
It’s typically found in:
- Anti-aging serums
- Eye creams
- Lifting creams
- Night treatments
Use it as directed—usually once or twice daily—on clean skin before moisturizers or sunscreens.
5. Is Syn TC the same as collagen?
No. Syn TC doesn’t contain collagen—it’s a peptide complex that stimulates the skin’s natural production of various types of collagen to improve structure and firmness.
6. How long does it take to see results with Syn TC?
Most users notice improvements in skin texture and firmness within 4 to 8 weeks of consistent use, depending on the product concentration and formulation.
7. Can Syn TC be combined with other active ingredients like retinol or vitamin C?
Yes, Syn®-TC can be combined with other anti-aging ingredients, but it’s best layered properly:
- Apply Syn®-TC serum first
- Follow with vitamin C (AM) or retinol (PM)
- Then moisturize
Always monitor your skin’s response and adjust based on sensitivity.
8. Is Syn TC safe during pregnancy or breastfeeding?
There’s no specific data suggesting Syn®-TC is harmful, but due to limited research on peptide use during pregnancy, it’s best to consult with a healthcare provider before using it.
9. What makes Syn TC different from other peptides like Matrixyl or Argireline?
Unlike single-action peptides, Syn®-TC is a multi-collagen boosting complex, targeting five key collagen types for a broader and deeper rejuvenating effect. Matrixyl mostly targets collagen I and III, while Argireline mimics Botox-like effects on muscle tension.
10. Are there any side effects?
Syn TC is considered non-irritating and non-sensitizing. Side effects are rare but may include mild redness or tingling on sensitive skin. Discontinue use if irritation persists.
Derek Hansen –
Top-tier peptide complex. I used it on some stubborn wrinkles and saw great improvement
Olivia Brooks –
This is luxury skincare in a bottle. My clients love it and I personally use it too!
Noah Carter –
The blend is powerful and feels premium. Worth the price tag
Hannah Martinez –
This product completely upgraded my skincare routine. Firm, hydrated, and glowing skin
James Kelly –
I like the science behind this complex. Been using it daily and my skin elasticity has improved a lot.