Oxytocin is a hormone and neurotransmitter naturally produced in the hypothalamus and released by the posterior pituitary gland. It plays a crucial role in several biological functions related to childbirth, bonding, and reproduction.
Key Functions of Oxytocin
1. Childbirth (Labor Induction)
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Oxytocin stimulates uterine contractions during labor.
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It is commonly administered (synthetically) under the brand name Pitocin to induce or strengthen labor in medical settings.
2. Postpartum Hemorrhage Control
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After delivery, oxytocin helps contract the uterus to minimize bleeding.
3. Breastfeeding
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Oxytocin triggers the milk let-down reflex, helping breast milk move from the alveoli to the nipples during nursing.
4. Social Bonding & Emotions
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Often dubbed the “love hormone” or “cuddle hormone”, oxytocin plays a role in:
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Parent-infant bonding
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Trust and empathy
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Romantic and sexual connection
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Medical Uses of Synthetic Oxytocin
| Use Case | Purpose |
|---|---|
| Labor induction | Initiates or strengthens uterine contractions |
| Postpartum bleeding | Reduces risk of hemorrhage after birth |
| Incomplete miscarriage | Assists in uterine evacuation |
| Off-label use | Studied in autism, anxiety, and trust-related disorders, though not FDA-approved for these |
Dosage & Administration
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Route: Typically intravenous (IV) or intramuscular (IM) in clinical settings.
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Dosing: Depends on the indication (e.g., induction vs. hemorrhage control); dosing should be done by trained healthcare professionals only.
Side Effects
Common
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Nausea
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Vomiting
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Mild uterine cramping
Serious (requires medical attention)
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Uterine hyperstimulation (can lead to fetal distress)
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Water intoxication (oxytocin has antidiuretic effects in high doses)
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Hypotension or hypertension
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Allergic reactions
Precautions & Contraindications
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Not to be used in non-medically indicated labor (e.g., purely elective induction before 39 weeks).
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Contraindicated in:
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Cephalopelvic disproportion
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Fetal distress when delivery is not imminent
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Hypersensitivity to oxytocin
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Application
Biochem/physiol Actions
Oxytocin Acetate is a synthetic form of the naturally occurring nonapeptide hormone oxytocin, primarily synthesized in the hypothalamus. It plays a crucial role in stimulating uterine contractions during childbirth and facilitating lactation by promoting milk ejection. Beyond its reproductive functions, oxytocin is significant in modulating social behaviors such as bonding, sexual and maternal behaviors, and aggression. It has also been implicated in various non-social behaviors, including learning, anxiety, feeding, and pain perception.
Chemical Information:
- CAS Number: 6233-83-6
- Molecular Formula: C₄₅H₇₀N₁₂O₁₄S₂
- Molecular Weight: 1,067.25 g/mol
Synonyms:
- α-Hypophamine Acetate
- Oxytocic Hormone Acetate
Biological Activity: Oxytocin Acetate functions as a stress-coping molecule with anti-inflammatory, antioxidant, and protective effects, particularly in response to adversity or trauma.
Solubility:
- DMSO: 14 mg/mL
- Ethanol: 5 mg/mL
- PBS (pH 7.2): 5 mg/mL
Storage Conditions: Store at -20°C to maintain stability and potency.
Oxytocin Supplement
Oxytocin supplements are formulated to mimic or support the effects of the natural hormone oxytocin—often called the “bonding” or “love” hormone. While the body produces oxytocin naturally during touch, intimacy, and childbirth, supplements are designed to enhance emotional connection, reduce social anxiety, and promote feelings of trust and relaxation.
Typically available in nasal spray, sublingual, or homeopathic forms, oxytocin supplements are often used in wellness and behavioral health settings. Though not FDA-approved for treating psychiatric or social disorders, some users report benefits in stress management, relationship intimacy, and social bonding.
Potential Benefits
- Promote emotional bonding and connection
- Ease social discomfort and stress
- Support intimacy in relationships
- Enhance mood and relaxation
Common Forms
- Nasal Spray – Rapid absorption via nasal mucosa
- Sublingual Tablets – For slow release under the tongue
- Homeopathic Blends – Typically herbal or amino acid-based (non-hormonal)
Not a Medical Treatment
Oxytocin supplements should not be used as a substitute for professional medical or psychiatric care. They are not approved to treat autism, anxiety, or depression, though they are sometimes marketed as mood enhancers or intimacy boosters.
Frequently Asked Questions (FAQs)
1. Is oxytocin safe during labor?
Yes, when administered by professionals in controlled settings. However, it carries risks if overused or mismanaged.
2. Can oxytocin be used for emotional bonding disorders?
It is being studied for conditions like autism and social anxiety, but it is not approved for these uses yet.
3. How fast does oxytocin work?
When used IV during labor induction, contractions can begin within a few minutes.
4. Can men produce oxytocin?
Yes — oxytocin plays a role in male orgasm, bonding, and emotional regulation.
5. Is oxytocin addictive?
No — it does not produce chemical addiction like opioids or stimulants, but it can reinforce social behaviors.
| Quantity | 2mg * 10 vials, 5mg * 10 vials |
|---|
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Tyler Brooks –
Interesting effect on mood and social bonding. Subtle but effective
Natalie West –
Tested for behavioral response. Impressive results and no side effects
Justin Reed –
Improved mood and connection with others. A very curious compound
Brooke Allen –
Warm, positive vibe after use. Really interesting for emotional regulation
Caleb Watson –
Used in a neuro-lab setting. Results aligned with published studies.