N Acetyl Selank Amidate 15mg

N Acetyl Selank Amidate 15mg is a potent, research-grade peptide derivative of Selank—a synthetic analog of the human tuftsin peptide. Engineered with both N-acetylation and amidation modifications, this version offers enhanced stability, bioavailability, and binding affinity, making it ideal for advanced nootropic and anxiolytic research applications.

Designed specifically for investigational and laboratory use, this peptide has attracted interest due to its potential to influence the GABAergic system, promote neuroprotection, and support cognitive performance under stress.

Key Features:

• Purity: ≥ 99% (HPLC-tested)
• Molecular Modifications: N-Acetylation and C-terminal amidation for increased peptide longevity
• Form: Lyophilized powder (15mg)
• Grade: USA-manufactured, research-only compound
• Solubility: Water-soluble for easy reconstitution

Potential Research Areas:

• Anxiolytic and anti-stress effects
• Improvement of memory and learning capacity
• Modulation of the immune response
• Neuroprotection and brain repair mechanisms
• GABA receptor regulation

Why Use the Amidated Version?

The amidated form of Selank (Selank Amidate) provides increased resistance to enzymatic degradation and allows for a more sustained biological effect. Coupled with N-acetylation, the peptide remains intact longer during experiments, delivering consistent results in neurobehavioral studies.

Selank Peptide

Selank is a synthetic neuropeptide developed as a nootropic and anxiolytic agent. Structurally, it’s a heptapeptide analog of tuftsin, an immune-modulating peptide found naturally in the human body. Originally created by the Institute of Molecular Genetics of the Russian Academy of Sciences, Selank has undergone decades of research for its cognitive-enhancing, anti-anxiety, and immune-supportive properties.

How Selank Works (Mechanism of Action)

Selank’s mechanisms are not entirely mapped, but several pathways are strongly supported in research:

• Modulation of GABA: Selank appears to influence the GABAergic system, which plays a central role in regulating mood and anxiety.
• Stabilization of Enkephalins: It helps stabilize endogenous opioid peptides, improving stress resilience.
• Monoamine Modulation: Studies suggest it may balance levels of dopamine, norepinephrine, and serotonin.
• BDNF Upregulation: Early findings suggest Selank may increase Brain-Derived Neurotrophic Factor, supporting neuroplasticity and repair.

Research-Based Benefits of Selank Peptide

Cognitive and Emotional Research:

• Reduces anxiety without sedation
• Enhances focus, clarity, and learning
• Boosts memory retention
• Reduces fatigue from stress or overexertion

Immunomodulatory Research:

• Improves immune system balance
• Enhances antiviral defense responses
• Potential adjunct for stress-related immune suppression

Selank Peptide vs. Traditional Anxiolytics

Unlike benzodiazepines, which risk sedation and dependency, Selank exhibits anxiolytic properties without impairing motor function or alertness. This has made it a subject of great interest in labs studying non-habit-forming anxiety solutions.

Modified Forms of Selank (e.g., N-Acetyl Selank Amidate)

To improve its pharmacokinetic profile, researchers have developed variants such as:

• N-Acetyl Selank: Improved membrane permeability
• Selank Amidate: Enhanced resistance to enzymatic breakdown
• N-Acetyl Selank Amidate: Combines both modifications for maximal potency and duration

Conclusion

Selank is an innovative peptide offering a wide range of research possibilities in neuropsychiatry, nootropics, and immunology. Its ability to influence mood, cognition, and immune resilience makes it a unique target for ongoing investigations into non-toxic, non-addictive neurological therapies.

 N Acetyl Selank

N-Acetyl Selank is a chemically enhanced version of the original Selank peptide, featuring an N-acetylation modification at the N-terminal end of the molecule. This structural tweak is designed to improve stability, resistance to enzymatic degradation, and bioavailability in research settings.

Like standard Selank, it is a synthetic heptapeptide derived from tuftsin, with a strong research focus on anxiolytic, nootropic, and immunomodulatory properties. The acetylation makes it more suitable for studies where extended peptide activity or enhanced receptor binding is required.

Key Characteristics of N-Acetyl Selank:

• Structure: Modified with an acetyl group at the N-terminus
• Purpose: Enhances half-life and stability in research conditions
• Mechanism of Interest: GABA modulation, monoamine regulation, BDNF expression
• Research Focus Areas:
  • Anxiety reduction
  • Stress response and mood stabilization
  • Cognitive enhancement
  • Immune system regulation

Why Use the Acetylated Version?

The acetylation helps protect the peptide from enzymatic breakdown, allowing it to remain active in biological systems for longer periods. This leads to more reliable and prolonged experimental outcomes, especially in in vivo studies.

Conclusion

N-Acetyl Selank builds on the foundation of Selank by offering superior stability and potential efficacy in experimental applications. It is a prime candidate for laboratories investigating advanced nootropic compounds or seeking non-sedative anxiolytics for preclinical research.

Frequently Asked Questions – N-Acetyl Selank Amidate 15mg

1. What is N-Acetyl Selank Amidate 15mg?
N-Acetyl Selank Amidate 15mg is a modified version of the Selank peptide designed for enhanced stability and bioavailability. It features both N-acetylation and C-terminal amidation, making it more resistant to enzymatic degradation and potentially more effective in neurocognitive and anxiolytic research models.

2. What is the difference between regular Selank and N-Acetyl Selank Amidate?
The standard Selank peptide is effective but has a shorter half-life in biological systems. The N-acetyl group at the N-terminus and the amidated tail at the C-terminus increase resistance to degradation, resulting in longer activity, stronger receptor affinity, and more consistent experimental results.

3. What is this peptide commonly researched for?
N-Acetyl Selank Amidate is primarily studied for its potential in:

• Anxiety reduction
• Cognitive enhancement
• Neuroprotection
• Mood stabilization
• Immune modulation

It is often explored in research relating to stress-induced cognitive decline and immune dysregulation.

4. Is N-Acetyl Selank Amidate 15mg safe for human use?
No. This product is strictly for laboratory research purposes only. It is not approved for human or veterinary use and should not be used outside of controlled, ethical research environments.

5. How is N-Acetyl Selank Amidate typically stored?
For optimal stability, the lyophilized peptide should be stored at -20°C in a dry, dark environment. After reconstitution, it should be stored in a sterile, sealed vial and kept refrigerated at 2–8°C, ideally used within a short period to maintain research integrity.

6. Can this peptide be reconstituted with bacteriostatic water?
Yes. Most researchers reconstitute N-Acetyl Selank Amidate 15mg using bacteriostatic water or sterile saline, depending on the study design. Solubility is generally good due to its modified structure.

7. Does the amidation and acetylation affect biological function?
Yes. These modifications significantly increase peptide half-life, reduce breakdown, and enhance binding efficiency to target receptors, making it preferable in studies requiring prolonged or sustained neurochemical effects.

8. Where is this product manufactured?
N-Acetyl Selank Amidate 15mg is typically synthesized in GMP-certified facilities in the USA for research-grade distribution, ensuring high purity (≥99%) and compliance with industry standards for investigational use.