Ghk Tripeptide 3

GHK Tripeptide 3 is a powerful skin-rejuvenating peptide known for its ability to stimulate collagen and elastin production, improve skin texture, and reduce the appearance of fine lines and wrinkles. Structurally similar to the naturally occurring GHK-Cu, this tripeptide enhances cellular regeneration and promotes firmer, smoother, and more youthful-looking skin. Commonly used in advanced skincare formulations, GHK Tripeptide 3 supports wound healing, boosts antioxidant defense, and helps restore skin elasticity for a revitalized complexion. Ideal for anti-aging and repair-focused treatments.

AHK Tripeptide 3 200mg

AHK, also called tripeptide, is a three-amino-acid-long peptide primarily found in the blood of mammals. It is usually attached to copper and has effects on a wide range of cells including fibroblasts and endothelial cells. It is a well-known anti-oxidant in research circles and is currently being investigated in animal models for its ability to combat hair loss.

Research Application:

AHK has been extensively investigated in animal models for its effect on hair growth, wound healing, and tissue regeneration. It has been studied heavily by the cosmetics industry, in animal and in vitro models, for its ability to tighten skin, improve skin elasticity, reduce photodamage (a.k.a. melisma), lessen fine lines and wrinkles, and boost cell shedding in the stratum corneum (the top layer of skin)

What Is AHK Tripeptide?

AHK tripeptide is a small peptide made of just three amino acids – Alanine, Histidine, and Lysine. It is sometimes referred to just as “tripeptide,” though that particular term can be applied to any three-amino-acid-long peptide. The cosmeceutical industry refers to AHK as DNA repair factor in some cases. AHK is often, but not always, complexed with copper, making it AHK-Cu.

What Does AHK Do?

AHK has been found, in animal and in vitro research, to activate fibroblasts. Fibroblasts are responsible for much of the extracellular matrix (proteins outside of cells) production that occurs in skin and other connective tissues (e.g. bones, muscle, etc.). Fibroblasts are primarily responsible for the production of collagen and elastin. Collage gives skin strength and also acts to attract water, making skin smoother and suppler. Elastin gives skin an ability to stretch and helps to prevent the formation of fine lines and wrinkles. Together, collagen and elastin are heavily involved in preventing skin aging, with both quantity and quality of these proteins falling off as we age. Studies of the effects of AHK on collagen and elastin indicate that it increases collagen type I production by more than 300%.

Another effect of AHK is on the production of vascular endothelial growth factor and transforming growth factor beta-1. Endothelial cells line the inside of blood vessels and are responsible for much of the first stages of blood vessel growth. Transforming growth factor beta-1 regulates cell growth, differentiation, and death. By increasing the secretion of endothelial growth factor and decreasing the secretion of transforming growth factor beta-1, AHK can stimulate blood vessel growth, particularly in the skin.

AHK Research Against Hair Loss

One of the reasons that hair loss occurs is that the follicles from which hairs grow die. This can happen for a number of reasons, but the primary reason is a loss of blood supply to the follicle. Research in animal models shows that AHK can stimulate blood vessel growth and help to maintain the health of existing blood vessels through the mechanisms described above. Research on human dermal cells grown in the laboratory shows that AHK stimulates the growth of blood vessels in and around hair follicles. This results in the elongation of hair follicles and the proliferation of a type of cell called a dermal papilla cell (DPC). DPCs act as shepherds of hair follicles, helping them access nutrients and ensuring that they remain healthy. Animal research indicates that by encouraging blood vessel growth and promoting the survival of DPCs, AHK can protect existing hair follicles and even help to regrow hair

AHK Cu vs GHK Cu

AHK Cu and GHK Cu are both copper peptides used in skincare and hair growth formulations, but they serve slightly different purposes.

GHK Cu (Glycyl-L-Histidyl-L-Lysine-Copper):
Widely recognized for its regenerative properties, GHK Cu promotes collagen production, improves skin firmness, reduces inflammation, and accelerates wound healing. It is a go-to ingredient for anti-aging skincare, known to restore skin elasticity and reduce fine lines.

AHK Cu (Alanine-Histidine-Lysine-Copper):
Primarily used in hair care, AHK Cu stimulates hair follicle growth, strengthens existing hair, and prolongs the hair growth phase. It also possesses anti-inflammatory properties, making it beneficial for treating scalp irritation and supporting healthy hair density.

Key Difference:
While both peptides are copper-bound and aid in tissue repair and anti-inflammatory response, GHK Cu is more skin-focused, whereas AHK Cu is specially targeted for hair growth and scalp health. Their distinct amino acid structures lead to different biological activities, making each ideal for specific cosmetic and therapeutic applications.

FAQs – GHK Tripeptide 3

1. What is GHK Tripeptide 3?
GHK Tripeptide 3 is a synthetic peptide used in skincare to promote collagen production, enhance skin regeneration, and improve overall skin appearance.

2. How does GHK Tripeptide 3 benefit the skin?
It helps reduce fine lines, firm the skin, improve elasticity, and accelerate wound healing. It also supports cellular repair and reduces inflammation.

3. Is GHK Tripeptide 3 the same as GHK-Cu?
No, while both are tripeptides, GHK-Cu is a copper-bound version of the GHK peptide. GHK Tripeptide 3 is a modified form with similar skin-repair benefits but may not include copper.

4. Can GHK Tripeptide 3 be used daily?
Yes, most formulations containing GHK Tripeptide 3 are safe for daily use as part of your skincare routine.

5. Is GHK Tripeptide 3 safe for sensitive skin?
Generally, yes. It is well-tolerated and gentle, but a patch test is recommended if you have very sensitive skin or allergies.

6. What types of products contain GHK Tripeptide 3?
It’s commonly found in serums, anti-aging creams, and advanced skin-repair formulations.

7. How long does it take to see results from GHK Tripeptide 3?
Visible improvements may begin in 2–4 weeks with consistent use, depending on skin condition and product concentration.