COA Thymosin Beta-4 Fragment (1-4) (Ac-SDKP) 500mcg (60 Capsules) Certificate
5 Amino 1MQ (5‑amino‑1‑methylquinolinium) is a synthetic small molecule designed to inhibit the enzyme NNMT (nicotinamide N‑methyltransferase). Primarily researched for its effects on metabolism, fat breakdown, mitochondrial function, and cellular energy regulation
HPLC Thymosin Beta-4 Fragment (1-4) (Ac-SDKP) 500mcg (60 Capsules) Certificate
MS Thymosin Beta-4 Fragment (1-4) (Ac-SDKP) 500mcg (60 Capsules)Certificate
Key Features
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Potent NNMT inhibitor: Blocks NNMT activity to favor fat burning over storage by reducing lipogenesis in adipocytes.
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Boosts NAD⁺ availability: Elevated NAD⁺ supports mitochondrial energy production, DNA repair, and activates longevity-related pathways like SIRT1.
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Metabolic and weight-management support: Preclinical studies report reversal of diet-induced obesity and improved metabolic profiles in animal models.
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Muscle sparing: Tends to promote fat loss while preserving lean muscle mass .
5 amino 1mq side effects
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Gastrointestinal discomfort – nausea, vomiting, diarrhea are frequently mentioned.
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Mild dizziness or headaches – often described as transient and mild .
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Fatigue or drowsiness – some users report tiredness or occasional lethargy .
Allergic & Cardiovascular Reactions
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Allergic responses – rare cases of hives, itching, skin rash, and swelling have been reported.
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Cardiovascular signs – elevated blood pressure, faster heart rate, and palpitations have been noted in limited reports.
Additional Possible Effects
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Sleep disturbances or insomnia – possibly if taken late in the day, likely due to enhanced cellular energy.
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General digestive changes – mild bloating or altered bowel habits occasionally reported.
Scope & Severity
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Most side effects are mild to moderate, typically short-lived.
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Long-term safety data in humans is lacking, so more extensive studies are needed.
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Current info is largely based on preclinical models and early anecdotal experiences, so effects in humans may vary.
Recommendations & Precautions
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Medical oversight is strongly advised – particularly for those with preexisting conditions or on other medications.
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Start cautiously – begin with a low dose (e.g., 50 mg/day), monitoring for any reactions before considering gradual increases.
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Optimize timing – avoid evening doses to reduce the chance of sleep disruption.
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Discontinue and consult if experiencing severe effects like chest pain, significant mood changes, or intense allergic responses.
While 5‑Amino‑1MQ appears relatively well-tolerated in early use, its safety for long-term human use remains unverified. Caution, monitoring, and professional advice are essential when using this compound.
5 amino 1mq benefits
1. Enhanced Fat Metabolism & Weight Loss
5‑Amino‑1MQ targets the enzyme NNMT in adipose tissue, reducing lipogenesis and increasing fat breakdown in fat cells by up to 70%, according to lab studies on adipocytes. In mice on a high-fat diet, pairing this compound with a low-fat diet reversed obesity and improved liver health.
2. Increased Energy & Endurance
By inhibiting NNMT, 5‑Amino‑1MQ raises NAD⁺ levels, which fuels mitochondrial function and energy metabolism. In aged mice, it boosted grip strength by ~25% in sedentary animals and ~60% when combined with exercise; it also significantly extended daily running distance.
3. Muscle Preservation & Performance
Compared with exercise alone, 5‑Amino‑1MQ further improved muscle strength and reduced fat content within muscle cells in animal studies—highlighting its role in muscle quality and regeneration.
4. Anti‑Aging & Cellular Resilience
Higher NAD⁺ levels activate longevity-associated proteins like SIRT1, promoting DNA repair, mitochondrial maintenance, and reduced inflammation. This suggests potential anti-aging effects, with slowed muscular and metabolic decline over time.
5. Metabolic Regulation & Disease Protection
By improving fat metabolism and elevating NAD⁺, 5‑Amino‑1MQ may enhance insulin sensitivity and support healthier glucose regulation. Increased NNMT activity has been linked to obesity and type 2 diabetes risk. Additionally, preliminary research indicates potential support for cardiovascular and kidney health .
Frequently Asked Questions (FAQs) – 5-Amino-1MQ
1. What is 5-Amino-1MQ?
5-Amino-1MQ is a small molecule compound that inhibits the enzyme NNMT (Nicotinamide N-Methyltransferase). It is primarily studied for its potential to improve metabolism, increase energy levels, and support fat loss.
2. How does 5-Amino-1MQ work?
It works by blocking NNMT, an enzyme involved in fat cell metabolism and NAD+ consumption. Inhibiting NNMT helps increase cellular NAD+ levels, supporting fat breakdown, energy production, and longevity-related cellular pathways.
3. What are the benefits of using 5-Amino-1MQ?
Potential benefits include:
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Enhanced fat loss
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Increased energy and endurance
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Muscle preservation
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Anti-aging support (via NAD+ and SIRT1 activation)
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Improved metabolic function
4. Are there any side effects?
Some users report mild side effects such as nausea, headaches, dizziness, or fatigue. In rare cases, allergic reactions or elevated heart rate may occur. Always consult a healthcare professional before use.
5. Is 5-Amino-1MQ safe for human use?
5-Amino-1MQ is considered a research chemical and is not FDA-approved for medical or dietary use. Its safety and efficacy in humans are still being evaluated, and it should only be used under professional supervision or in research contexts.
6. What is the recommended dosage?
There is no official human dosage. However, research-grade capsules are often sold in 50 mg doses, with suggested usage ranging from 50–100 mg per day. Dosing should be discussed with a qualified health provider.
7. How long does it take to see results?
Some users report noticeable changes in energy and fat loss within 2–4 weeks. However, results may vary based on dosage, individual metabolism, and lifestyle.
8. Can I combine 5-Amino-1MQ with other supplements?
Some users combine it with NAD+ precursors like NMN or NR. However, interactions are not well studied, so speak to your healthcare provider before combining with other substances.
9. Is 5-Amino-1MQ legal?
Yes, it is legal to purchase for research purposes in many countries. However, it is not approved as a dietary supplement or medication and should not be marketed for consumption.
10. Where can I buy 5-Amino-1MQ?
It is available from various research chemical suppliers and peptide vendors online. Be sure to purchase from reputable sources that provide lab testing and certificates of analysis (COAs).
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