5-Amino 1MQ

5-Amino-1MQ (5-amino-1-methylquinolinium) is a synthetic small molecule studied in biochemical and metabolic research, particularly in relation to nicotinamide N-methyltransferase (NNMT) enzyme activity. Research focuses on its potential role in cellular metabolism and NAD+ pathway regulation.

This compound is supplied in capsule and liquid formats, strictly for laboratory research under controlled settings. It is not approved for human or veterinary use.

Product Specifications

• Compound Name: 5-Amino-1MQ
• Concentration: 100 mg per capsule
• Quantity: 60 capsules per container
• Form Options: Capsule or liquid solution (for analytical purposes)
• Storage Conditions: Store at 2–8°C in a dry, dark environment
• Intended Use: Research use only (RUO). Not for diagnostic, therapeutic, or clinical applications.

Research Context

5-Amino-1MQ is evaluated in vitro and in preclinical models for its potential impact on metabolic enzyme regulation, particularly NNMT activity. NNMT is known to participate in methylation cycles and cellular energy balance, including NAD+ biosynthesis.

Research studies have focused on investigating parameters such as:

• NAD+ biosynthesis and availability
• SIRT1-related activity (in vitro)
• Methyl donor retention
• Cellular energy expenditure
• Mitochondrial signaling and oxidative metabolism

These studies are ongoing. All findings are preliminary and pertain strictly to experimental research models, not clinical applications.

Regulatory and Compliance Notice

• FDA Status: Not approved by the FDA for medical, diagnostic, or therapeutic use.
• Intended Use: For research use only. Supplied exclusively to qualified laboratories and licensed research institutions.
• Administration: Not for human or veterinary consumption or administration.
• Handling Requirements: Use only with appropriate personal protective equipment (PPE) and within controlled laboratory environments such as a chemical fume hood or biosafety cabinet.

Quality & Assurance

HVY Research ensures all batches are prepared in sterile, controlled facilities and undergo routine testing for identity and consistency. All research personnel must follow standard laboratory safety protocols.

Disclaimer

This product is for research purposes only. No claims are made regarding safety, efficacy, or intended use in humans or animals. This information is provided strictly for scientific and informational purposes.

Frequently Asked Questions (FAQ): 5-Amino 1MQ

1. What is 5-Amino 1MQ?

5-Amino 1MQ is a small molecule research compound that inhibits nicotinamide N-methyltransferase (NNMT). By reducing NNMT activity, it may influence fat metabolism, energy production, and cellular repair mechanisms. It is being studied for its potential impact on weight loss, insulin sensitivity, and longevity pathways.

2. How does 5-Amino 1MQ work?

5-Amino 1MQ works by blocking NNMT, an enzyme linked to energy expenditure and fat storage. Inhibiting NNMT may increase NAD⁺ levels (crucial for mitochondrial health and metabolism), which in turn can enhance energy metabolism and potentially reduce adipose tissue accumulation.

3. What are the potential benefits of 5-Amino 1MQ?

Although research is still in early stages, possible investigational benefits include:

• Support for weight and fat loss
• Improved insulin sensitivity
• Enhanced cellular metabolism
• Mitochondrial function support
• Anti-aging or longevity-related effects (via NAD⁺ pathway modulation)

Note: These are based on animal and preclinical studies, not yet confirmed in human trials.

4. Is 5-Amino 1MQ FDA-approved?

No. 5-Amino 1MQ is not approved by the FDA for medical use, treatment, or diagnosis. It is strictly intended for research purposes only, and should not be used in humans outside of controlled studies.

5. How is 5-Amino 1MQ typically administered in research?

In laboratory settings, 5-Amino 1MQ is commonly used in capsule or injectable form, depending on the design of the experiment. Dosage, frequency, and duration vary based on the study’s goals and animal models used. No standardized human dose exists.

6. Are there side effects or safety concerns?

Because human trials are limited or nonexistent, side effects of 5-Amino 1MQ are not well documented. The lack of toxicology or long-term safety data means risks are unknown. Use in humans carries potential health hazards and is strongly discouraged without formal medical oversight.

7. Can 5-Amino 1MQ be used for weight loss?

While preclinical studies suggest it may help regulate fat metabolism, 5-Amino 1MQ is not a weight loss drug and should not be marketed or used as one. Claims of weight loss benefits are unproven and speculative.

8. Is 5-Amino 1MQ legal to buy?

In most jurisdictions, 5-Amino 1MQ can be legally purchased for laboratory research only. However, selling or using it as a dietary supplement or medicine is illegal and violates regulatory laws in countries like the U.S., UK, Australia, and EU member states.

9. What’s the difference between 5-Amino 1MQ and NMN or NAD⁺?

• 5-Amino 1MQ is an NNMT inhibitor that indirectly affects NAD⁺ levels.
• NMN (Nicotinamide Mononucleotide) is a direct precursor to NAD⁺.
  While both may support cellular energy and metabolism, 5-Amino 1MQ works upstream, altering the enzyme that regulates NAD⁺ usage and clearance, not direct NAD⁺ production.

10. Who is 5-Amino 1MQ intended for?

It is intended solely for scientific research involving cell cultures, animal models, or other non-human systems. It is not suitable for personal, recreational, or clinical use.

11. Where can I find more scientific data on 5-Amino 1MQ?

Look for peer-reviewed journals or databases such as:

• PubMed
• Google Scholar
• NIH.gov
  Search terms like “NNMT inhibitors,” “5-Amino 1MQ metabolism,” or “5-Amino 1MQ weight loss mice study.”