Tesamorelin, Ipamorelin (Blend)Certificate
Tesamorelin
Tesamorelin is a growth hormone releasing hormone analog that has been shown to increase IGF-1 levels in men by an average of 181 micrograms/liter. It binds and stimulates human GHRH receptors with similar potency as endogenous GHRH. It has a host of other benefits including nootropic effects and reducing triglycerides. Tesamorelin research has subsequently been shown to decrease carotid intima media thickness (cIMT), visceral adipose tissue (VAT), and C-reactive proteins (CRP) in a recent study. It has not been shown to significantly affect other pituitary hormones and their respective mechanisms in the body. Additionally, studies have shown it to improve cognitive function for healthy older adults and also for people with mild cognitive impairment who are at an increased risk of progressing to Alzheimer’s disease.
HPLC Tesamorelin, Ipamorelin (Blend) Certificate
MS Tesamorelin, Ipamorelin (Blend) Certificate
Ipamorelin
Ipamorelin is a selective GH-Secretagogue and ghrelin receptor agonist. The potency of ghrelin stimulation can be compared to GHRP6 with less appetite stimulation properties. However, unlike other GH-Secretagogues this pentapeptide doesn’t release the same volumes of cortisol, acetylcholine, prolactin and aldosterone. It is for this reason Ipamorelin has been considered the first selective GH-Secretagogue
Ipamorelin and Tesamorelin exhibits minimal side effects, low oral and excellent subcutaneous bioavailability in mice. Per kg dosage in mice does not scale to humans. Ipamorelin and Tesamorelin are for sale at Peptide Sciences is limited to educational and scientific research only, not for human consumption. Only buy Ipamorelin and Tesamorelin if you are a licensed researcher.
Tesamorelin vs Ipamorelin
Tesamorelin and Ipamorelin are both peptide-based growth hormone secretagogues, but they differ in structure, function, and clinical application.
- Tesamorelin is a synthetic analog of GHRH (Growth Hormone-Releasing Hormone), primarily used in clinical settings to reduce excess abdominal fat in HIV-infected patients with lipodystrophy. It promotes natural growth hormone (GH) secretion and has strong lipolytic (fat-reducing) effects. Tesamorelin is FDA-approved for specific medical use.
- Ipamorelin, on the other hand, is a selective ghrelin receptor agonist that stimulates GH release with minimal impact on cortisol or prolactin levels. It is widely used in wellness and anti-aging protocols for muscle growth, fat loss, and improved recovery, often in combination with other peptides like CJC-1295.
Summary of Differences:
- Mechanism: Tesamorelin mimics GHRH; Ipamorelin mimics ghrelin.
- Use: Tesamorelin is for clinical fat reduction; Ipamorelin is for performance and anti-aging.
- Approval: Tesamorelin is FDA-approved; Ipamorelin is commonly used off-label.
Both peptides enhance GH levels, but Tesamorelin is more focused on metabolic benefits, while Ipamorelin offers broader wellness and regenerative support.
Tesamorelin Ipamorelin Blend
The Tesamorelin Ipamorelin blend combines two powerful peptides that synergistically enhance the body’s natural growth hormone (GH) production through different mechanisms. Tesamorelin acts as a GHRH (Growth Hormone-Releasing Hormone) analog, stimulating the pituitary gland to release GH in a natural pulsatile manner. Ipamorelin, a selective ghrelin receptor agonist, further amplifies GH release without affecting cortisol or prolactin levels.
When used together, this blend provides a potent, balanced approach to GH stimulation, ideal for individuals seeking benefits such as:
- Fat reduction, particularly visceral fat
- Increased lean muscle mass
- Improved recovery and performance
- Enhanced sleep and well-being
- Anti-aging and regenerative effects
This combination is popular in advanced peptide therapy protocols for its clinical fat-loss benefits from Tesamorelin and wellness-supporting properties from Ipamorelin, making it an effective solution for those aiming to optimize hormone levels naturally and safely
Tesamorelin Ipamorelin Dosage
The Tesamorelin Ipamorelin dosage varies depending on individual goals, body composition, and medical supervision. When used together, these peptides create a synergistic effect that enhances growth hormone release while minimizing side effects.
- Typical Tesamorelin Dosage: 1–2 mg per day, administered via subcutaneous injection, usually in the evening to mimic the body’s natural GH pulse.
- Typical Ipamorelin Dosage: 100–300 mcg per day, also delivered subcutaneously, often taken 1–3 times daily depending on the protocol.
When used in combination, the Tesamorelin + Ipamorelin blend is commonly administered once daily in a pre-measured blend to ensure convenience and optimal GH response.
Key Considerations:
- Always follow medical guidance for dosage adjustments.
- Ideal injection time is before bed or post-workout to support recovery and natural GH rhythms.
- Long-term use should include periodic hormone level monitoring.
Proper dosing is essential for maximizing fat loss, muscle growth, and anti-aging benefits while minimizing potential risks.
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